Chemical Resistant Gloves

Protect your hands from hazardous substances with our comprehensive collection of chemical resistant gloves. Whether you're in a laboratory, a workshop, or just doing some serious cleaning, our durable and reliable nitrile, latex, and vinyl gloves provide the essential barrier you need to work safely and confidently.

14 products

  • N5MLGS-CS, N5MLGM-CS, N5MLGL-CS, N5MLGXL-CS, N5MLGXXL-CS
5 MilGlove Powder Free Nitrile Gloves, Case - UNISAFE GLOVES N5MLGS-CS, N5MLGM-CS, N5MLGL-CS, N5MLGXL-CS, N5MLGXXL-CS, 5 MilGlove Powder Free Nitrile Gloves, Case - UNISAFE GLOVES

    $64.99

    As low as
    $57.99
  • PB500S-CS, PB500M-CS, PB500L-CS, PB500XL-CS, PB500XXL-CS, PitBull Powder Free Black Nitrile Exam Gloves, Case - UNISAFE GLOVES N6MLGS-CS, N6MLGM-CS, N6MLGL-CS, N6MLGXL-CS, N6MLGXXL-CS, N7SM-CS, N7MD-CS, N7LG-CS, N7XL-CS, DTN7-CS, DTN7M-CS, DTN7L-CS, DTN7XL-CS, GT766S-CS, GT766M-CS, GT766L-CS, GT766XL-CS, GT766XL-CS, PB500S-CS, PB500M-CS, PB500L-CS, PB500XL-CS, PB500XXL-CS, Powder Free Black Nitrile Exam Gloves, Case - UNISAFE GLOVES

    $94.99

    As low as
    $74.99
  • N6MLGS-CS, N6MLGM-CS, N6MLGL-CS, N6MLGXL-CS, N6MLGXXL-CS, 6 MilGlove Industrial Grade Powder Free Black Nitrile Gloves, Case - UNISAFE GLOVES N6MLGS-CS, N6MLGM-CS, N6MLGL-CS, N6MLGXL-CS, N6MLGXXL-CS, N7SM-CS, N7MD-CS, N7LG-CS, N7XL-CS, DTN7-CS, DTN7M-CS, DTN7L-CS, DTN7XL-CS, GT766S-CS, GT766M-CS, GT766L-CS, GT766XL-CS, GT766XL-CS, PB500S-CS, PB500M-CS, PB500L-CS, PB500XL-CS, PB500XXL-CS, Powder Free Black Nitrile Exam Gloves, Case - UNISAFE GLOVES

    $79.99

    As low as
    $64.99
  • Sale -13% GZ700S-CS, GZ700M-CS, GZ700L-CS, GZ700XL-CS, GZ700XXL-CS, GZ700S-Pallet, GZ700M-Pallet, GZ700L-Pallet, GZ700XL-Pallet, GZ700XXL-Pallet,  Glovezilla 8.5 Mil Dual-Layer Heavy-Duty Nitrile Gloves w/ Raised Diamond Texture - UNISAFE GLOVES GZ700S-CS, GZ700M-CS, GZ700L-CS, GZ700XL-CS, GZ700XXL-CS, GZ700S-Pallet, GZ700M-Pallet, GZ700L-Pallet, GZ700XL-Pallet, GZ700XXL-Pallet, Glovezilla 8.5 Mil Dual-Layer Heavy-Duty Nitrile Gloves w/ Raised Diamond Texture - UNISAFE GLOVES

    $159.99 $139.99

    As low as
    $119.99
  • PY700S-CS, PY700M-CS, PY700L-CS, PY700XL-CS PY700XXL-CS, Black Python 8 Mil Heavy-Duty Powder Free Industrial Grade Nitrile Gloves w/Diamond Texture, Case - UNISAFE GLOVES PY700S-CS, PY700M-CS, PY700L-CS, PY700XL-CS PY700XXL-CS, Black Python 8 Mil Heavy-Duty Powder Free Industrial Grade Nitrile Gloves w/Diamond Texture, Case - UNISAFE GLOVES

    $134.99

    As low as
    $114.99
  • TGPF7S-CS, TGPF7M-CS, TGPF7L-CS, TGPF7XL-CS, TGPF7XXL-CS, TGPF7S-Pallet, TGPF7M-Pallet, TGPF7L-Pallet, TGPF7XL-Pallet, TGPF7XXL-Pallet, Pallet (96 Cases) of TopGrip HD 7 Mil Powder Free Black Nitrile Exam Gloves - UNISAFE GLOVES, TopGrip HD 7 Mil Powder Free Black Nitrile Exam Gloves, Case - UNISAFE GLOVES TGPF7S-CS, TGPF7M-CS, TGPF7L-CS, TGPF7XL-CS, TGPF7XXL-CS, TGPF7S-Pallet, TGPF7M-Pallet, TGPF7L-Pallet, TGPF7XL-Pallet, TGPF7XXL-Pallet, Pallet (96 Cases) of TopGrip HD 7 Mil Powder Free Black Nitrile Exam Gloves - UNISAFE GLOVES, TopGrip HD 7 Mil Powder Free Black Nitrile Exam Gloves, Case - UNISAFE GLOVES

    $106.99

    As low as
    $86.99
  • N7SM-CS, N7MD-CS, N7LG-CS, N7XL-CS, DTN7-CS, DTN7M-CS, DTN7L-CS, DTN7XL-CS, 7 MilGlove HD Powder Free Black Nitrile Gloves, Case - UNISAFE GLOVES N8SM-CS, N8MD-CS, N8LG-CS, N8XL-CS, N8XXL-CS, N7SM-CS, N7MD-CS, N7LG-CS, N7XL-CS, DTN7-CS, DTN7M-CS, DTN7L-CS, DTN7XL-CS, Diamond Textured Powder Free Black Nitrile Gloves - UNISAFE GLOVES

    $84.99

  • CH500S-CS, CH500M-CS, CH500L-CS, CH500XL-CS, CH500XXL-CS, Copperhead 8 Mil Heavy-Duty Powder Free Industrial Grade Orange Nitrile Gloves w/Diamond Texture, Case - UNISAFE GLOVES CH500S-CS, CH500M-CS, CH500L-CS, CH500XL-CS, CH500XXL-CS, Copperhead 8 Mil Heavy-Duty Powder Free Industrial Grade Orange Nitrile Gloves w/Diamond Texture, Case - UNISAFE GLOVES

    $134.99

    As low as
    $114.99
  • TGPFS-CS, TGPFM-CS, TGPFL-CS, TGPFXL-CS, TGPFXXL-CS, TopGrip Powder Free Industrial Nitrile Gloves, Case - UNISAFE GLOVES TGPFS-CS, TGPFM-CS, TGPFL-CS, TGPFXL-CS, TGPFXXL-CS, VF500S-CS, VF500M-CS, VF500L-CS, VF500XL-CS, VF500XXL-CS, TGPFS-Pallet, TGPFM-Pallet, TGPFL-Pallet, TGPFXL-Pallet, TGPFXXL-Pallet, VF500S-Pallet, VF500M-Pallet, VF500L-Pallet, VF500XL-Pallet, VF500XXL-Pallet, Blue Disposable Powder Free Nitrile Gloves

    $94.99

    As low as
    $74.99
  • Sale -31% N8SM-CS, N8MD-CS, N8LG-CS, N8XL-CS, N8XXL-CS,
8 MilGlove HD Powder Free Nitrile Gloves w/ Diamond Texture Grip, Case - UNISAFE GLOVES N8SM-CS, N8MD-CS, N8LG-CS, N8XL-CS, N8XXL-CS, 8 MilGlove HD Powder Free Nitrile Gloves w/ Diamond Texture Grip - UNISAFE GLOVES

    $129.99 $89.99

  • GT766S-CS, GT766M-CS, GT766L-CS, GT766XL-CS, GT766XL-CS, Gotham Powder Free Black Nitrile Exam Gloves, Case - UNISAFE GLOVES N6MLGS-CS, N6MLGM-CS, N6MLGL-CS, N6MLGXL-CS, N6MLGXXL-CS, N7SM-CS, N7MD-CS, N7LG-CS, N7XL-CS, DTN7-CS, DTN7M-CS, DTN7L-CS, DTN7XL-CS, GT766S-CS, GT766M-CS, GT766L-CS, GT766XL-CS, GT766XL-CS, PB500S-CS, PB500M-CS, PB500L-CS, PB500XL-CS, PB500XXL-CS, Powder Free Black Nitrile Exam Gloves, Case - UNISAFE GLOVES

    $74.99

    As low as
    $64.99
  • Sale -47% GP888M-CS, GP888L-CS, Goprene Powder Free Industrial Grade Neoprene Gloves, Case - UNISAFE GLOVES GP888M-CS, GP888L-CS, Goprene Powder Free Industrial Grade Neoprene Gloves, Case - UNISAFE GLOVES

    $94.99 $49.99

  • UNI-HR1000S-CS, UNI-HR1000M-CS, UNI-HR1000L-CS, UNI-HR1000XL-CS, UNI-HR1000XXL-CS, Crowbar Heavy Duty 10 Mil Extended Cuff Nitrile Exam Gloves, Case - UNISAFE GLOVES UNI-HR1000S-CS, UNI-HR1000M-CS, UNI-HR1000L-CS, UNI-HR1000XL-CS, UNI-HR1000XXL-CS, Crowbar Heavy Duty 10 Mil Extended Cuff Nitrile Exam Gloves, Case - UNISAFE GLOVES

    $94.99

    As low as
    $74.99
  • ON600S-CS, ON600M-CS, ON600L-CS, ON600XL-CS, On Guard Powder Free Orange Nitrile Exam Gloves, Case - UNISAFE GLOVES ON600S-CS, ON600M-CS, ON600L-CS, ON600XL-CS,

    $94.99

    As low as
    $74.99

Heavy-Duty Chemical-Resistant Disposable Gloves

Industrial and Lab-Grade Hand Protection Shielding Against Harsh Chemicals, Solvents, and Acids

When handling aggressive chemical compounds, industrial solvents, oils, and hazardous fluids, standard disposable gloves are completely insufficient. Permeation and degradation can cause common materials to tear, swell, or dissolve, exposing skin to severe occupational hazards. Our industrial-grade chemical-resistant gloves are specifically engineered for automotive technicians, manufacturing plants, sanitation crews, and laboratory technicians who require maximum structural integrity, advanced puncture resistance, and a reliable barrier against aggressive chemical solutions.

  • Premium Chemical Permeation Defense: High-density synthetic formulations provide a heavy-duty defensive barrier against petroleum distillates, grease, hydraulic fluids, and mild acids.
  • Extreme Puncture & Abrasion Resistance: Thicker 8.0+ mil profiles deliver maximum structural tensile strength to resist punctures from rough tools, sharp metal parts, and industrial equipment.
  • Aggressive High-Grip Texturing: Features specialized raised diamond or micro-roughened surface textures to guarantee a non-slip grip when handling slick tools or oily components.
  • Extended Cuff Variants: Available in extended configurations to provide extra splash protection for the wrists and lower forearms.
  • Options Not Made with Natural Rubber Latex: Fully available in specialized synthetic nitrile configurations to protect sensitive employees from natural rubber allergy triggers in high-stress work settings.

Chemical-Resistant Glove Performance Applications

Industrial facilities demand hand protection that matches their precise chemical exposure levels. Utilizing an incorrect or weak material under harsh conditions compromises shop safety. Choosing targeted, high-mil protection ensures complete compliance and barrier confidence across every application:

Automotive, Fleet Maintenance & Mechanical Work

Automotive shops interface with brake fluids, motor oils, degreasers, and fuel additives daily. Standard thin gloves quickly degrade and swell when exposed to these hydrocarbons. Heavy-duty options, like our Glovezilla Heavy Duty Nitrile Gloves or our thick Black Python Nitrile Gloves, provide an exceptional barrier against petroleum-based fluids while giving mechanics the physical toughness needed to handle heavy machinery without tearing.

Industrial Sanitation, Cleaning & Janitorial Services

Commercial cleaning crews manage concentrated bleach solutions, caustic ammonia compounds, and specialized surface strippers. Heavy-duty black nitrile options, such as Black Python Nitrile, offer excellent chemical splash resistance, keeping hands completely shielded from caustic irritants during long sanitation and pressure-washing shifts.

Laboratory Research, Testing & Chemical Sorting

Laboratory technicians require flawless tactile precision alongside chemical splashing defenses. Our high-performance, high-mil nitrile and heavy-duty disposable latex configurations offer the exact touch feedback required to handle delicate glass pipettes and test tubes safely while maintaining reliable splash defenses against acids and chemical reagents.

Agricultural, Paint Sprayers & Coating Lines

Handling liquid fertilizers, pesticide concentrates, or oil-based paints requires extended coverage and reliable permeation resistance. Our heavy-duty industrial lineups protect workers from chemical absorption through the skin during chemical mixing and industrial spray applications.

How to Choose the Correct Chemical-Resistant Material

When selecting your facility's safety equipment, match the material compound and thickness to the severity of your chemical exposure:

  1. Nitrile Gloves (Oils, Fuels, & Solvents): The absolute top choice for industrial settings. Synthetic nitrile provides exceptional resistance to petroleum products, greases, diesel fuel, and general workshop solvents, while offering up to three times the puncture resistance of standard natural rubber.
  2. Latex Gloves (Maximum Elasticity & Fit): Premium disposable latex options, like our Diamondback HD, provide unmatched tactile sensitivity and tensile strength. They deliver a form-fitting, comfortable stretch that minimizes hand fatigue over long shifts while resisting punctures during precision assembly work.
  3. Mil-Thickness Considerations: For maximum safety around chemicals, look closely at the glove's thickness rating. Heavy industrial environments handling rough tools or abrasive chemicals should look for 8.0 mil to 8.5 mil options (such as our Glovezilla and Black Python series) to maximize wear times and tear resistance.
  4. Texture Profiles: When working around heavy lubricants or liquid solutions, smooth gloves can slip. Always opt for an aggressive raised diamond texture or an all-over micro-roughened surface to ensure tools stay locked in workers' hands.

Quick Reference: Industrial & Chemical Product Overview

Glovezilla Heavy Duty Nitrile Gloves

  • Material: Dual-Layer Nitrile (Not made with natural rubber latex)
  • Thickness: 8.5 mil
  • Key Benefit: Extreme puncture resistance, aggressive raised diamond texture for secure grip.
  • Best For: Automotive mechanics, industrial machinery maintenance, and heavy solvent handling.

Black Python Nitrile Gloves

  • Material: Nitrile (Not made with natural rubber latex)
  • Thickness: 8.0 mil
  • Key Benefit: Sleek black material that masks grease stains, heavy-duty thick barrier profile.
  • Best For: Commercial sanitation, heavy fleet maintenance, and industrial chemical cleaning.

Diamondback HD Latex Gloves

  • Material: Premium Natural Rubber Latex
  • Thickness: 8.0 mil
  • Key Benefit: Extreme elasticity, maximum contour fit to reduce hand fatigue with a dependable physical grip.
  • Best For: Detailed laboratory chemical testing, precision parts manufacturing, and high-dexterity painting tasks.

Why Buy Industrial Safety Gloves From UniSafe?

UniSafe Gloves provides commercial safety procurement teams, plant managers, and fleet maintenance shops with direct access to high-performance hand protection by the case and full pallet. Here is why industrial operations partner with us:

  • Direct-to-Factory Bulk Pricing Tiers: Eliminate the steep retail distributor markup. We provide aggressive wholesale pricing tiers on bulk case orders to preserve your safety budget.
  • Strict Quality Control & Uniform Spec Standards: We partner with premium manufacturers to ensure that every box delivered contains true-to-spec mil thickness and robust cuff durability, minimizing workplace waste.
  • Fast Logistics & Deep Stocking Reserves: We keep massive inventory levels of heavy-duty black, orange, and green industrial gloves to ensure your supply lines stay stocked without interruption.
  • Full Fleet Compliance Support: Our team can provide the specific product matching, bulk billing options, and tracking updates required by corporate purchasing guidelines.

Frequently Asked Questions

Can disposable nitrile gloves resist all types of industrial chemicals?

No disposable glove is universally resistant to every chemical compound. High-quality synthetic nitrile is exceptionally resistant to petroleum distillates, greases, motor oils, hydraulic fluids, and mild acids. However, strong ketones or highly concentrated volatile acids can degrade thin materials rapidly. Always consult a specific manufacturer chemical permeation guide if your facility handles highly specialized volatile compounds.

How does mil thickness affect chemical permeation times?

Mil thickness dictates the breakthrough time—the duration it takes a specific chemical to penetrate through the glove material to the skin. A thicker option like our Black Python Nitrile (8.0 mil) or Glovezilla (8.5 mil) provides a significantly longer breakthrough safety window against fluids compared to a standard thin glove, making it essential for prolonged contact with heavy solvents or greases.

What is the benefit of a raised diamond texture in chemical environments?

When hands are covered in slick motor oils, chemical lubricants, or liquid solutions, standard smooth gloves completely lose physical traction. An aggressive raised diamond texture pattern, found on our Glovezilla lineups, physically channels fluids away from the glove's surface contact points, maintaining a reliable, non-slip grip on heavy hand tools and slippery parts.

Are these chemical-resistant gloves safe for employees with skin conditions or allergies?

Yes. Our primary synthetic industrial chemical-resistant lines—including Glovezilla and Black Python—are manufactured entirely without natural rubber latex. Moving your warehouse or shop away from powder-filled options minimizes the threat of severe Type I allergic reactions and helps mitigate contact skin irritation during extended shifts.



Why should my auto shop choose black or orange nitrile over standard industrial blue gloves?

Black and high-visibility orange are highly practical for industrial trades. Black gloves, like Black Python, mask unsightly grease stains, carbon soot, and dark oils, keeping your service crew looking completely professional. High-visibility orange options like Copperhead are heavily favored by industrial safety directors because they dramatically increase hand visibility in low-light engine bays or heavy manufacturing lines, helping to prevent accidental pinch-point injuries.

Do these heavy-duty gloves cause hand fatigue during long manufacturing shifts?

Stiff industrial materials can restrict hand movement, causing severe fatigue and cramping over an 8-hour shift. If hand strain is a major concern for your precision cutting or assembly teams, a high-elasticity disposable latex option like our Diamondback HD (8.0 mil) delivers a highly comfortable, ergonomic stretch that moves naturally with your palm and fingers.

What is the difference between chemical degradation and chemical permeation?

Degradation occurs when a chemical physically destroys the glove material, causing it to visibly shrink, swell, soften, or dissolve on your hand. Permeation is a much more hazardous process where a chemical absorbs into and travels through the glove material on a microscopic level without causing any visible physical changes to the rubber, emphasizing the absolute need for proper mil thickness choices.

How do I choose between heavy-duty disposable latex and nitrile for chemical environments?

Choose nitrile (like Glovezilla or Black Python) if your primary concern is resisting petroleum-based fluids, hydrocarbons, greases, motor oils, and heavy solvents. Choose a heavy-duty disposable latex (like Diamondback HD) if your workers need maximum tactile dexterity and extreme elasticity for handling precision lab components, fine tools, or intricate painting lines where natural rubber's flexible properties shine.

Are all nitrile gloves chemical resistant?

While nitrile gloves offer excellent chemical resistance, their effectiveness varies depending on the specific chemical and the glove's thickness. Always check the manufacturer's chemical resistance chart for compatibility.

How do I know when to change my gloves?

Gloves should be changed immediately if they are torn, punctured, or show signs of degradation such as swelling, cracking, or discoloration. For chemical exposure, gloves should be replaced after a period of use to prevent permeation.

Can I reuse chemical resistant gloves?

Our disposable chemical-resistant gloves are designed for single-use to ensure maximum safety and hygiene. Reusing gloves can compromise the integrity of the barrier and expose you to contaminants.

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